Assuming you’re using a press brake for bending, the general rule of thumb for minimum bend radius is 1-2 times the material thickness. It sounds like you should go for bottom bending, since you talk about edge alignment (reasonably low tolerance) and a tight inside bend radius. Bottom bending is more accurate and has less springback than air bending. I would also guess that bottom bending is probably better for components that will be exposed to vibration and fatigue. However, the reality is that bottom bending is more expensive than air bending, so it’s gonna have to be a tradeoff about how much that accuracy is worth to you. It’s also slower.